Papers

2022

**Inducible plasmid copy number control for synthetic biology in commonly used E. coli strains**

Shivang Joshi, Chentao Yong, Andras Gyorgy
Nature Communications

A blueprint for a synthetic genetic feedback optimizer

Andras Gyorgy, Amor Menezes, Murat Arcak
Revise and Resubmit in Nature Communications

Evolutionary selection between constitutive and feedback regulation

Andras Gyorgy
Under review

2021

Context-dependent stability
and robustness of genetic toggle switches with leaky promoters

Andras Gyorgy
Life, Special Issue on Synthetic Genetic Elements, Devices, and Systems

Stability and robustness of
unbalanced genetic toggle switches in the presence of scarce resources

Chentao Yong, Andras Gyorgy
Life, Special Issue on Synthetic Biology

2020

Self-activation attenuates the adverse effects of scarce resources on genetic switches

Andras Gyorgy
IEEE Control Systems Letters
IEEE Conference on Decision and Control

Genetic optimizer module
for synthetic biology

Andras Gyorgy, Amor Menezes, Murat Arcak
IFAC World Congress

Scarcity of cellular resources decreases the robustness of toggle switches to noise

Andras Gyorgy
American Control Conference

A practical step-by-step guide for quantifying retroactivity in gene
networks

Andras Gyorgy
Book chapter in Design, Construction and Modelling of Synthetic Gene Circuits, Springer

2019

How cell-to-cell heterogeneity and scarce resources shape the population-level stability profile of toggle switches

Andras Gyorgy
IEEE Conference on Decision and Control

Leveraging resources competition for part characterization in cell-free
extracts

Andras Gyorgy
Foundations of Systems Biology in Engineering

Bistability requires better balanced toggle switches in the presence of
competition for shared cellular resources

Andras Gyorgy
American Control Conference

2018

Sharing resources can lead to monostability in a network of bistable toggle switches

Andras Gyorgy
IEEE Control Systems Letters

Optimal experiment design and
leveraging competition for shared resources in cell-free extracts

Wolfgang Halter, Frank Allgower, Richard M. Murray, Andras Gyorgy
IEEE Conference on Decision and Control

2017

Pattern formation over multigraphs

Andras Gyorgy, Murat Arcak
IEEE Transactions on Network Science and Engineering

Pattern formation in large-scale networks with asymmetric connections

Andras Gyorgy
IFAC World Congress

2016

Quantifying resource competition and its effects in the TX-TL system

Andras Gyorgy, Richard M. Murray
IEEE Conference on Decision and Control

Creating single-copy genetic circuits

Jeong-Wok Lee, Andras Gyorgy, D. Ewen Cameron, Nora Pyenson, Kyeong Rok Choi, Jeffrey C. Way, Pamela A. Silver, Domitilla Del Vecchio, James J. Collins
Cell

2015

Isocost lines describe the cellular economy of genetic circuits

Andras Gyorgy, Jose I. Jimenez, John Yazbek, Hattie Chung, Ron Weiss, Domitilla Del Vecchio
Biophysical Journal

Bounding the effect of retroactivity in the presence of parameter uncertainty

Thomas P. Prescott, Andras Gyorgy
American Control Conference

2014

Modular composition of gene transcription networks

Andras Gyorgy, Domitilla Del Vecchio
PLoS Computational Biology

Limitations and trade-offs in gene expression due to competition for shared cellular resources

Andras Gyorgy, Domitilla Del Vecchio
IEEE Conference on Decision and Control

2013

How slaves affect a master module in gene transcription networks

Andras Gyorgy, Domitilla Del Vecchio
IEEE Conference on Decision and Control

2012

Retroactivity to the input in complex gene transcription networks

Andras Gyorgy, Domitilla Del Vecchio
IEEE Conference on Decision and Control

2011

Quasi-model-based control of type 1 diabetes mellitus

Andras Gyorgy, Levente Kovacs, Peter Szalay, Daniel A. Drexler, Balazs Benyo, Zoltan Benyo
Journal of Electrical and Computer Engineering

Robust servo control of a novel type 1 diabetic model

Levente Kovacs, Balazs Kulcsar, Andras Gyorgy, Zoltan Benyo
Optimal Control Applications and Methods

Quasi-model-based control of type 1 diabetes mellitus

Levente Kovacs, Andras Gyorgy, Peter Szalay, Daniel A. Drexler, Balazs Benyo, Zoltan Benyo
IFAC World Congress

2010

ANFIS regulated type 1 diabetic model for different glucose absorption scenarios

Andras Gyorgy, Peter Szalay, Daniel A. Drexler, Zoltan Benyo, Balazs Benyo, Andras Kovacs, Levente Kovacs
IEEE Conference on Intelligent Engineering Systems